Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CDKN2A loss and PIK3CA mutation in myoepithelial-like metaplastic breast cancer.

The Journal of pathology - 1 Jul 2018

Bartels Stephan, van Luttikhuizen Jana Lisa, Christgen Matthias, Mägel Lavinia, Luft Angelina, Hänzelmann Sonja, Lehmann Ulrich, Schlegelberger Brigitte, Leo Fabian, Steinemann Doris, Kreipe Hans

Abstract excerpt

Metaplastic breast carcinoma comprises a heterogeneous group of tumours with poorly understood pathogenesis. A subset of metaplastic breast cancers show myoepithelial differentiation and constitute a morphological spectrum with ill-defined borders from fibromatosis-like spindle cell carcinoma to myoepithelial carcinoma. In a series of 34 metaplastic breast cancers with spindle cell and myoepithelial...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers, Tumor
Share to Breast Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Differentiation

Share to Chromosomes, Human, Pair 9

Share to Class I Phosphatidylinositol 3-Kinases

Share to Cyclin-Dependent Kinase Inhibitor p16

Share to Epithelial Cells

Share to Metaplasia

Source

Identifiers

PMID: 29708279
DOI: 10.1002/path.5091

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CDKN2A loss and PIK3CA mutation in myoepithelial-like metaplastic breast cancer.PMID 29708279Read ↗

An Update on the Molecular Pathology of Metaplastic Breast CancerSemantic proximity Read ↗

Adenomyoepitheliomas of the Breast Frequently Harbor Recurrent Hotspot Mutations in PIK3-AKT Pathway-related Genes and a Subset Show Genetic Similarity to Salivary Gland Epithelial-Myoepithelial CarcinomaSemantic proximity Read ↗

Adenomyoepithelial tumors of the breast: molecular underpinnings of a rare entity.Semantic proximity Read ↗

Assessment of HMGA2 and PLAG1 rearrangements in breast adenomyoepitheliomasSemantic proximity Read ↗

Phenotypic and molecular dissection of metaplastic breast cancer and the prognostic implicationsSemantic proximity Read ↗

A comprehensive overview of metaplastic breast cancer: Features and treatments.Semantic proximity Read ↗

Molecular pathology of phyllodes tumours of the breast-much more than MED12.Semantic proximity Read ↗

Problematic breast tumors reassessed in light of novel molecular data.Semantic proximity Read ↗

Microglandular adenosis: a non-obligate precursor of triple-negative breast cancer?Semantic proximity Read ↗

Adenoid cystic carcinomas constitute a genomically distinct subgroup of triple‐negative and basal‐like breast cancersSemantic proximity Read ↗

High rate of PIK3CA mutations but no TP53 mutations in low-grade adenosquamous carcinoma of the breast.Semantic proximity Read ↗

Solid-Basaloid Adenoid Cystic Carcinoma of the Breast: An Aggressive Subtype Enriched for Notch Pathway and Chromatin Modifier Mutations With MYB Overexpression.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.