Article
High rate of PIK3CA mutations but no TP53 mutations in low-grade adenosquamous carcinoma of the breast.
Histopathology - 1 Aug 2018
Bataillon Guillaume, Fuhrmann Laetitia, Girard Elodie, Menet Emanuelle, Laé Marick, Capovilla Mathieu, Treilleux Isabelle, Arnould Laurent, Penault-Llorca Frederique, Rouzier Roman, Marchiò Caterina, Bieche Ivan, Vincent-Salomon Anne
Abstract excerpt
AIMS: Low-grade adenosquamous carcinoma of the breast (LGASC) is a rare variant of metaplastic carcinoma characterised by a favourable outcome and histologically composed of glandular and squamous elements in a spindle cell background typically associated with a lymphocytic stromal reaction. Because of its rarity, the immunophenotypic and genetic profile of LGASC has not been sufficiently characterised. The aim...
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