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Article

Targeting cancer through tumor-selective mRNA stabilization

2007-01-01

Abstract excerpt

The success of cancer gene therapy is hindered by various physiological barriers to therapeutic vector transport from the site of injection to the nucleus of all the tumor cells. The application of replicating viruses for the treatment of cancers can overcome this problem. But this approach is limited by normal tissue tolerance of toxicity determined by local concentration of transgene products and viral proteins....

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Identifiers and source

Literature Corpus work
4560dc37-a009-5557-855f-92dae496b585
DOI
10.21954/ou.ro.0000fb3a
Open publication

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