Development of telomerase targeted gene therapy for treatment of cancer

Abstract excerpt

Gene therapy is an area that is currently developing for treatment of various congenital and acquired diseases. The basic concept is that a transgene is expressed in a target cell resulting in alleviation of disease. In general there are certain obstacles limiting gene therapy regardless of the target disease. These include restriction of transgene expression to target cells, inadequate transgene expression and in...

Topics

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• Antigen-Presenting Cells
• Antigens, Neoplasm
• CAR-T cell therapy research
• Genetic Therapy
• Mutation
• Oncolytic Virotherapy
• Viral Infectious Diseases and Gene Expression in Insects
• Virus-based gene therapy research

Identifiers and source

Literature Corpus work

9fd7396a-172c-5b30-af60-cfbc18585883

DOI

10.5525/gla.thesis.74178