Article

Profiling of Driver Mutations Identified Rare Compound Mutations Sensitive to Second-generation EGFR-TKI in Lung Adenocarcinoma Patients

2022-11-15

Abstract excerpt

<h4>Background: </h4> Lung adenocarcinoma (LUAD) is the most predominant histological subtype of lung cancer characterized by driver mutations detected in a substantial proportion of the cases. Tyrosine kinase inhibitors (TKIs) are standard care for the patients with these mutations. In this study, we evaluated the efficiency of an NGS-based 8-gene test in selecting TKIs-sensitive Chinese LUAD patients who are tre...

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Literature Corpus work: 4544d1b6-7fee-52be-a6d1-787eb1f36c84
DOI: 10.21203/rs.3.rs-2242483/v1

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