Article

Reconstitution of autophagosomal membrane tethering reveals that Atg11 can bind and cluster vesicles on cargo mimetics

2023-12-19

Abstract excerpt

<h4>ABSTRACT</h4> Autophagy is essential for the degradation of mitochondria from yeast to humans. Mitochondrial autophagy in yeast is initiated when the selective autophagy scaffolding protein Atg11 is recruited to mitochondria through its interaction with the selective autophagy receptor Atg32. This also results in the recruitment of small 30 nm vesicles that fuse to generate the initial autophagosomal membrane...

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Literature Corpus work: 44e436c7-4b79-5f83-95b5-ff5e4254e878
DOI: 10.1101/2023.12.19.572332

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