Article
Lipidation of the LC3/GABARAP family of autophagy proteins relies on a membrane-curvature-sensing domain in Atg3.
Nature cell biology - 1 May 2014
Nath Sangeeta, Dancourt Julia, Shteyn Vladimir, Puente Gabriella, Fong Wendy M, Nag Shanta, Bewersdorf Joerg, Yamamoto Ai, Antonny Bruno, Melia Thomas J
Abstract excerpt
The components supporting autophagosome growth on the cup-like isolation membrane are likely to be different from those found on closed and maturing autophagosomes. The highly curved rim of the cup may serve as a functionally required surface for transiently associated components of the early act...
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