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Automatic colocalization of high resolution MALDI MSI and Raman imaging applied to cardiac tissue of Fabry disease mouse models

2025-12-01

Abstract excerpt

Understanding early molecular changes in biological tissues is crucial for diagnosing pathological and genetic diseases and for elucidating their underlying mechanisms. However, localized molecular alterations of low molecular-weight compounds are not inferred from conventional staining or genetic methods. Here, we established a multimodal imaging approach that integrates Raman spectroscopy and atmospheric pressur...

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Literature Corpus work
44dceca8-454f-5148-867c-3f1de2e09d02
DOI
10.1101/2025.11.27.690907
Open publication

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Automatic colocalization of high resolution MALDI MSI and Raman imaging applied to cardiac tissue of Fabry disease mouse modelsDOI 10.1101/2025.11.27.690907
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