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Label-free imaging and machine learning reveal cyclin-dependent kinase 6 (CDK6)-regulated metabolic phenotypes and beige potential in single preadipocytes.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy - 5 Dec 2026

Zhou Yixuan, Xu Yuelin, Cheng Siyao, Ni Xintao, Zhang Lu, Zhang Xin, Hou Xiaoli, Xia Daozong

Abstract excerpt

Cyclin-dependent kinase 6 (CDK6) regulates adipogenesis and beige fat formation, but its role in preadipocyte metabolism is unclear. The mouse embryonic fibroblast cell line 3 T3-L1 is a well-established preadipocyte model with high adipogenic potential under adipogenic stimulation. Here, we employed label-free, non-invasive Raman imaging to investigate the metabolic profile of 3 T3-L1 cells following CDK6...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42242144
DOI: 10.1016/j.saa.2026.128124

Genes

CDK6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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