Article

Generating Ensembles of Gene Regulatory Networks to Assess Robustness of Disease Modules

2020-07-12

Abstract excerpt

The use of biological networks such as protein-protein interaction and transcriptional regulatory networks is becoming an integral part of biological research in the genomics era. However, these networks are not static, and during phenotypic transitions like disease onset, they can acquire new “communities” of genes that carry out key cellular processes. Changes in community structure can be detected by maximizing...

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Literature Corpus work: 44dca0a6-317b-521c-b242-375f7745090f
DOI: 10.1101/2020.07.12.198747

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