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Article

Cancer mutationscape: revealing the link between modular restructuring and intervention efficacy among mutations.

NPJ systems biology and applications - 13 Jul 2024

Plaugher Daniel, Murrugarra David

Abstract excerpt

There is increasing evidence that biological systems are modular in both structure and function. Complex biological signaling networks such as gene regulatory networks (GRNs) are proving to be composed of subcategories that are interconnected and hierarchically ranked. These networks contain highly dynamic processes that ultimately dictate cellular function over time, as well as influence phenotypic fate...

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PMID: 39003264
DOI: 10.1038/s41540-024-00398-6
PMCID: PMC11246485

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