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Static All-Atom Energetic Mappings of the SARS-Cov-2 Spike Protein with Potential Latch Identification of the Down State Protomer

2020-05-12

Abstract excerpt

The SARS-Cov-2 virion responsible for the current world-wide pandemic Covid-19 has a characteristic Spike protein (S) on its surface that embellishes both a prefusion state and fusion state. The prefusion Spike protein (S) is a large trimeric protein where each protomer may be in a so-called Up state or Down state, depending on the configuration of its receptor binding domain (RBD). The Up state is believed to all...

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Identifiers and source

Literature Corpus work
44a0b575-20fc-548e-8166-9617594f8d8b
DOI
10.1101/2020.05.12.091090
Open publication

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Static All-Atom Energetic Mappings of the SARS-Cov-2 Spike Protein with Potential Latch Identification of the Down State ProtomerDOI 10.1101/2020.05.12.091090
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