Article
Filamentous Fungus-Produced Human Monoclonal Antibody Provides SARS-CoV-2 Protection in Hamster and Non-Human Primate Models
2023-06-26
Abstract excerpt
<title>Abstract</title> <p>Monoclonal antibodies are an increasingly important tool for prophylaxis and treatment of acute virus infections like those with SARS-CoV-2. However, their use is largely limited by the length of development, yield and high production costs, as well as the need for continuous adaptation to newly emerging virus variants. Here we have used the filamentous fungus expression system <italic>...
Topics
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- Animal health and immunology
- Antifungal resistance and susceptibility
- Influenza Virus Research Studies
- Monoclonal and Polyclonal Antibodies Research
- Toxin Mechanisms and Immunotoxins
- Transgenic Plants and Applications
- vaccines and immunoinformatics approaches
- Viral Infectious Diseases and Gene Expression in Insects
Identifiers and source
- Literature Corpus work
- 448a2dac-2c14-5416-b54c-97bd4e4934b2
- DOI
- 10.21203/rs.3.rs-2999911/v1
