Article

Plasma exosomes from individuals with type 2 diabetes drive breast cancer aggression in patient-derived organoids

2024-09-19

Abstract excerpt

Women with obesity-driven diabetes (T2D) are predisposed to more aggressive breast cancers, yet patient metabolic status does not fully inform current standards of care. We previously identified plasma exosomes as key mediators of intercellular communication and drivers of tumor progression; however, their effect on immune cells within the tumor microenvironment (TME) remains unclear. To model this exosomal signal...

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Literature Corpus work: 4487f86a-89d5-558f-9dfd-ca3ff4d896d2
DOI: 10.1101/2024.09.13.612950

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