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Ferroptosis and its role in cardiomyopathy

20 Jun 2022

Abstract excerpt

Heart disease is the leading cause of death worldwide. Cardiomyopathy is a disease characterized by the heart muscle damage, resulting heart in a structurally and functionally change, as well as heart failure and sudden cardiac death. The key pathogenic factor of cardiomyopathy is the loss of cardiomyocytes, but the related molecular mechanisms remain unclear. Ferroptosis is a newly discovered regulated form of...

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PMID: 35738177
DOI: 10.1016/j.biopha.2022.113279

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