Article
Toxicity of Amyloid-β Peptides Varies Depending on Differentiation Route of SH-SY5Y Cells
21 Aug 2019
Abstract excerpt
Alzheimer's disease (AD) is a currently incurable neurodegenerative disorder being the major form of dementia worldwide. AD pathology is initiated by cerebral aggregation of amyloid-β (Aβ) peptides in the form of amyloid plaques; however, the mechanism how Aβ peptide aggregates participate in the disease progression and neurodegeneration is still under debate. Human neuroblastoma cell line SH-SY5Y is a convenient...
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