Article
The formation of tau pore-like structures is prevalent and cell specific: possible implications for the disease phenotypes.
Acta neuropathologica communications - 29 May 2014
Lasagna-Reeves Cristian A, Sengupta Urmi, Castillo-Carranza Diana, Gerson Julia E, Guerrero-Munoz Marcos, Troncoso Juan C, Jackson George R, Kayed Rakez
Abstract excerpt
Pathological aggregation of the microtubule-associated protein tau and subsequent accumulation of neurofibrillary tangles (NFTs) or other tau-containing inclusions are defining histopathological features of many neurodegenerative diseases, which are collectively known as tauopathies. Due to confl...
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