Article

Quality control recommendations for RNASeq using FFPE samples based on pre-sequencing lab metrics and post-sequencing bioinformatics metrics

2022-03-21

Abstract excerpt

<h4>Background: </h4> Formalin-fixed, paraffin-embedded (FFPE) tissues have many advantages for identification of risk biomarkers, including wide availability and potential for extended follow-up endpoints. However, RNA derived from archival FFPE samples has limited quality. Here we identified parameters that determine which FFPE samples have the potential for successful RNA extraction, library preparation, and ge...

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Literature Corpus work: 441bbd16-f3f9-589e-a655-272386724755
DOI: 10.21203/rs.3.rs-1428294/v1

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