Article
Mining the archives: a cross-platform analysis of gene expression profiles in archival formalin-fixed paraffin-embedded (FFPE) tissue
2015-05-24
Abstract excerpt
Formalin-fixed paraffin-embedded (FFPE) tissue samples represent a potentially invaluable resource for transcriptomic-based research into the molecular basis of disease. However, use of FFPE samples in gene expression studies has been limited by technical challenges resulting from degradation of nucleic acids. Here we evaluated gene expression profiles derived from fresh-frozen (FRO) and FFPE mouse liver tissues u...
Topics
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- Adipose Tissue and Metabolism
- Bioinformatics and Genomic Networks
- Colorectal Cancer Treatments and Studies
- Epigenetics and DNA Methylation
- Gene expression and cancer classification
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Molecular Biology Techniques and Applications
- RNA modifications and cancer
Identifiers and source
- Literature Corpus work
- 68bbffdb-aa33-522b-b63f-5f3879731773
- DOI
- 10.1101/019794
