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Article

NLRP3: a new therapeutic target in alcoholic liver disease

13 Jul 2023

Abstract excerpt

The liver is in charge of a wide range of critical physiological processes and it plays an important role in activating the innate immune system which elicits the inflammatory events. Chronic ethanol exposure disrupts hepatic inflammatory mechanism and leads to the release of proinflammatory mediators such as chemokines, cytokines and activation of inflammasomes. The mechanism of liver fibrosis/cirrhosis involve...

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PMID: 37520548
DOI: 10.3389/fimmu.2023.1215333

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