Article

Glucose controls co-translation of structurally related mRNAs <i>via</i> the mTOR and eIF2 pathways in human pancreatic beta cells

2021-09-13

Abstract excerpt

<h4>ABSTRACT</h4> Pancreatic beta cell response to glucose is critical for the maintenance of normoglycemia. A strong transcriptional response was classically described in rodent models but, interestingly, not in human cells. In this study, we exposed human pancreatic beta cells to an increased concentration of glucose and analysed at a global level the mRNAs steady state levels and their translationalability. Po...

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Literature Corpus work: 4406255c-313a-53e4-ab7d-c6f711fe95e8
DOI: 10.1101/2021.09.13.460006

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Glucose controls co-translation of structurally related mRNAs <i>via</i> the mTOR and eIF2 pathways in human pancreatic beta cellsDOI 10.1101/2021.09.13.460006Read

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