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PLAC8, a new marker for human interstitial extravillous trophoblast cells, promotes their invasion and migration

15 Jan 2018

Abstract excerpt

Proper differentiation of trophoblast cells in the human placenta is a prerequisite for a successful pregnancy, and dysregulation of this process may lead to malignant pregnancy outcomes, such as preeclampsia. Finding specific markers for different types of trophoblast cells is essential for understanding trophoblast differentiation. Here, we report that placenta-specific protein 8 (PLAC8) is specifically...

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PMID: 29361555
DOI: 10.1242/dev.148932

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