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Single-cell transcriptomic profiling reveals diversity in human iNKT cells across hematologic tissues

28 Apr 2025

Abstract excerpt

iNKT cells are described-one resembling naive/precursor cells and another resembling Th1/17/NK-like cells, with predominant expression of CD8αα protein. These critical insights into the transcriptional heterogeneity of human iNKT cells will facilitate future functional studies and inform iNKT-based cellular therapy development.

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PMID: 40305288
DOI: 10.1016/j.celrep.2025.115587

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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