Article

Circulating Microvesicle-Associated Inducible Nitric Oxide Synthase Is a Novel Therapeutic Target to Treat Sepsis: Current Status and Future Considerations

2021-11-10

Abstract excerpt

<h4>Objective</h4> To determine if mitigating the harmful effects of circulating microvesicle-associated inducible nitric oxide (MV-A iNOS) in vivo increases the survival of challenged mice in three different mouse models of sepsis. <h4>Design</h4> The ability of anti-MV-A iNOS monoclonal antibodies (mAbs) to rescue challenged mice was assessed using three different mouse models of sepsis. <h4>Setting</h4> Th...

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Literature Corpus work: 433caa79-3a87-50f7-a9f4-76056b919b0a
DOI: 10.1101/2021.11.08.467816

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