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Article

Defining Parameters That Modulate Susceptibility and Protection to Respiratory Murine Coronavirus MHV1 Infection.

Journal of immunology (Baltimore, Md. : 1950) - 15 Feb 2024

Silva Elvia E, Moioffer Steven J, Hassert Mariah, Berton Roger R, Smith Matthew G, van de Wall Stephanie, Meyerholz David K, Griffith Thomas S, Harty John T, Badovinac Vladimir P

Abstract excerpt

Patients infected with SARS-CoV-2 experience variable disease susceptibility, and patients with comorbidities such as sepsis are often hospitalized for COVID-19 complications. However, the extent to which initial infectious inoculum dose determines disease outcomes and whether this can be used for immunological priming in a genetically susceptible host has not been completely defined. We used an established...

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Identifiers

PMID: 38149923
DOI: 10.4049/jimmunol.2300434
PMCID: PMC10872354

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CD4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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