Article

Cardiomyocyte-derived circulating extracellular vesicles allow a non-invasive liquid biopsy of myocardium in health and disease

2024-09-22

Abstract excerpt

<h4>SUMMARY</h4> The ability to track disease without tissue biopsy in patients is a major goal in biology and medicine. Here, we identify and characterize cardiomyocyte-derived extracellular vesicles in circulation (EVs; “cardiovesicles”) through comprehensive studies of induced pluripotent stem cell-derived cardiomyocytes, genetic mouse models, and state-of-the-art mass spectrometry and low-input transcriptomic...

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Literature Corpus work: 2b26ebe7-13ae-52e0-9e68-16823e685e5b
DOI: 10.1101/2024.09.19.24314009

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