Article

CDKL5 deficiency results in atypical subregion-specific expression of perineuronal nets during mouse visual critical period

2022-09-01

Abstract excerpt

<h4>ABSTRACT</h4> Perineuronal nets (PNNs) in the primary visual cortex (V1) are specialized extracellular matrix structures that form predominantly on parvalbumin+ GABAergic neurons, marking the closure of visual critical period plasticity. More recently, PNNs are used to characterize deficits in critical period plasticity in mouse models for neurodevelopmental disorders such as Rett syndrome, Fragile X syndrome...

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Literature Corpus work: 4313f5d7-25b6-55fe-a669-cf3b83009725
DOI: 10.1101/2022.08.31.505900

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