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Prostate cancer stem cell dynamics in the evolution of drug resistance

4 Jun 2025

Abstract excerpt

Prostate cancer remains a leading cause of cancer-related mortality in men worldwide, with tumor heterogeneity, therapy resistance, and lineage plasticity posing significant clinical challenges. Androgen deprivation therapy (ADT), while initially effective, often culminates in castration-resistant prostate cancer, may fueled by castration-resistant prostate cancer stem cells (CSCs) with adaptive self-renewal and...

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Cancer Cells and Metastasis
Prostate Cancer Treatment and Research

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 40465775
DOI: 10.1097/js9.0000000000002611

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