Article
Epithelial to mesenchymal transition is mechanistically linked with stem cell signatures in prostate cancer cells.
PloS one - 27 Aug 2010
Kong Dejuan, Banerjee Sanjeev, Ahmad Aamir, Li Yiwei, Wang Zhiwei, Sethi Seema, Sarkar Fazlul H
Abstract excerpt
BACKGROUND: Current management of patients diagnosed with prostate cancer (PCa) is very effective; however, tumor recurrence with Castrate Resistant Prostate Cancer (CRPC) and subsequent metastasis lead to poor survival outcome, suggesting that there is a dire need for novel mechanistic understanding of tumor recurrence, which would be critical for designing novel therapies. The recurrence and the metastasis of...
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