Article
Mechanism of inflammation in age-related macular degeneration: an up-to-date on genetic landmarks.
Mediators of inflammation - 1 Jan 2013
Parmeggiani Francesco, Sorrentino Francesco S, Romano Mario R, Costagliola Ciro, Semeraro Francesco, Incorvaia Carlo, D'Angelo Sergio, Perri Paolo, De Nadai Katia, Bonomo Roversi Elia, Franceschelli Paola, Sebastiani Adolfo, Rubini Michele
Abstract excerpt
Age-related macular degeneration (AMD) is the most common cause of irreversible visual impairment among people over 50 years of age, accounting for up to 50% of all cases of legal blindness in Western countries. Although the aging represents the main determinant of AMD, it must be considered a multifaceted disease caused by interactions among environmental risk factors and genetic backgrounds. Mounting evidence...
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