Article

Multiomics reveals persistence of obesity-associated immune cell phenotypes in adipose tissue during weight loss and subsequent weight regain

2021-08-20

Abstract excerpt

Most individuals do not maintain weight loss, and weight regain increases cardio-metabolic risk beyond that of obesity. Adipose inflammation directly contributes to insulin resistance; however, immune-related changes that occur with weight loss and weight regain are not well understood. Single cell RNA-sequencing was completed with CITE-sequencing and biological replicates to profile changes in murine immune subpo...

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Literature Corpus work: 42b19b77-b3e0-5bdb-8cdc-edaa475b6a80
DOI: 10.1101/2021.08.20.455954

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