Article

Single cell-resolved transcriptional dynamics of human subcutaneous adipose tissue during lifestyle- and bariatric surgery-induced weight loss

2025-01-31

Abstract excerpt

During sustained weight gain, human white adipose tissue undergoes dramatic remodeling that may compromise adipose tissue function and lead to obesity comorbidities such as cardiometabolic disease. These comorbidities can be at least partially reversed by weight loss; however, the degree to which human adipose tissue is remodeled during weight loss is currently unclear. Here, we have used snRNA-seq combined with b...

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Literature Corpus work: 0d1b4e29-1b18-5aa8-a452-eb0983b87eb0
DOI: 10.1101/2025.01.30.634294

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