Article

Towards molecular stratification of pediatric T-cell lymphoblastic lymphomas based on Minimal Disseminated Disease and<i>NOTCH1/FBXW7</i>mutational status: the French EURO-LB02 experience

2020-09-09

Abstract excerpt

While outcome for pediatric T lymphoblastic lymphoma (T-LBL) has improved with Acute Leukemia-type therapy, survival after relapse remains rare. Few prognostic markers have been identified and the value of Minimal Residual Disease (MRD) is less clear than in T-ALL. Mutations of NOTCH1 and/or FBXW7 ( N/F ) identify good prognosis T-LBL and both MRD and high-level Minimal Disseminated Disease (MDD) are reported to b...

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Literature Corpus work: 42a0de69-99ef-501c-b5f2-5d324002978e
DOI: 10.1101/2020.09.08.20189829

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