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Article

NUPR1 maintains autolysosomal efflux by activatingSNAP25transcription in cancer cells

13 Nov 2017

Abstract excerpt

In the advanced stages of cancer, autophagy is thought to promote tumor progression through its ability to mitigate various cellular stresses. However, the details of how autophagy is homeostatically regulated in such tumors are unknown. Here, we report that NUPR1 (nuclear protein 1, transcriptional regulator), a transcriptional coregulator, is aberrantly expressed in a subset of cancer cells and predicts low...

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PMID: 29130426
DOI: 10.1080/15548627.2017.1338556

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