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Epigenetic age acceleration links atherogenic dyslipidaemia, inflammageing and frailty with adverse cardiovascular outcomes in older adults (UFO): a lipid-metabolome and epigenetic clock analysis

2025-06-10

Abstract excerpt

<h4>Summary</h4> <h4>Background</h4> Frailty and chronic inflammatory diseases are known risk factors for adverse outcomes and have been associated with epigenetic age acceleration (EAA), a quantitative estimation of biological age based on DNA methylation. We investigated the interrelationships between EAA, atherogenic dyslipidaemia and frailty; determined the best performing epigenetic clock for EAA estimation o...

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Literature Corpus work
d99e09b0-8a7c-5184-a08e-2e789cf7a5fc
DOI
10.1101/2025.06.09.25329276
Open publication

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Epigenetic age acceleration links atherogenic dyslipidaemia, inflammageing and frailty with adverse cardiovascular outcomes in older adults (UFO): a lipid-metabolome and epigenetic clock analysisDOI 10.1101/2025.06.09.25329276
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