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Metformin in aging and aging-related diseases: clinical applications and relevant mechanisms

1 Jan 2022

Abstract excerpt

Aging is a natural process, which plays a critical role in the pathogenesis of a variety of diseases, i.e., aging-related diseases, such as diabetes, osteoarthritis, Alzheimer disease, cardiovascular diseases, cancers, obesity and other metabolic abnormalities. Metformin, the most widely used antidiabetic drug, has been reported to delay aging and display protective effect on attenuating progression of various...

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PMID: 35401820
DOI: 10.7150/thno.71360

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