Article
Aberrant ROS Served as an Acquired Vulnerability of Cisplatin-resistant Lung Cancer
2021-01-08
Abstract excerpt
<title>Abstract</title> <p><bold>Background</bold>Lung cancer has become a global health issue in recent decades. Despite of high rate of resistance, cisplatin-base chemotherapy is still the main treatment of lung cancer patients who are not suitable for TKI-based targeted therapy and immunotherapy. Thus, overcoming cisplatin resistance is urgently needed.<bold>Methods</bold>A small panel is established to screen...
Topics
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- Cancer, Hypoxia, and Metabolism
- Cancer-related gene regulation
- Chemotherapy-induced cardiotoxicity and mitigation
- Chemotherapy-induced organ toxicity mitigation
- Ferroptosis and cancer prognosis
- Genomics, phytochemicals, and oxidative stress
- Glutathione Transferases and Polymorphisms
- RNA modifications and cancer
Identifiers and source
- Literature Corpus work
- 427b43c2-2959-5791-88a9-709d0bee893d
- DOI
- 10.21203/rs.3.rs-141062/v1
