Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Roles of ROS in Cancer Heterogeneity and Therapy

1 Jan 2017

Abstract excerpt

Cancer comprises a group of heterogeneous diseases encompassing high rates of morbidity and mortality. Heterogeneity, which is a hallmark of cancer, is one of the main factors related to resistance to chemotherapeutic agents leading to poor prognosis. Heterogeneity is profoundly affected by increasing levels of ROS. Under low concentrations, ROS may function as signaling molecules favoring tumorigenesis and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipose Tissue and Metabolism
Share to Cancer, Hypoxia, and Metabolism
Share to Redox biology and oxidative stress

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29123614
DOI: 10.1155/2017/2467940

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Roles of ROS in Cancer Heterogeneity and TherapyPMID 29123614Read ↗

ROS in cancer therapy: the bright side of the moon.Semantic proximity Read ↗

Oxidative Stress and Cancer: Advances and ChallengesSemantic proximity Read ↗

Reactive Oxygen Species and its Manipulation Strategies in Cancer TreatmentSemantic proximity Read ↗

Cancer cell killing via ROS: To increase or decrease, that is the questionSemantic proximity Read ↗

Oxidative Stress in Cancer Therapy: Friend or Enemy?Semantic proximity Read ↗

The Interplay of Reactive Oxygen Species, Hypoxia, Inflammation, and Sirtuins in Cancer Initiation and ProgressionSemantic proximity Read ↗

Redox control in cancer development and progressionSemantic proximity Read ↗

ROS and the DNA damage response in cancerSemantic proximity Read ↗

Mitochondrial ROS in cancer: initiators, amplifiers or an Achilles' heel?Semantic proximity Read ↗

Targeting Oxidatively Induced DNA Damage Response in Cancer: Opportunities for Novel Cancer TherapiesSemantic proximity Read ↗

Targeting CSCs in Tumor Microenvironment: The Potential Role of ROS-Associated miRNAs in Tumor AggressivenessSemantic proximity Read ↗

Reactive oxygen species (ROS) are a key determinant of cancer's metabolic phenotype.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.