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Cancer cell killing via ROS: To increase or decrease, that is the question

1 Dec 2008

Abstract excerpt

Reactive oxygen species (ROS) act as a second messenger in cell signaling and are essential for various biological processes in normal cells. Any aberrance in redox balance may relate to human pathogenesis including cancers. Since ROS are usually increased in cancer cells due to oncogene activation, relative lack of blood supply or other variances and ROS do involve in initiation, progression and metastasis of...

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PMID: 18981733
DOI: 10.4161/cbt.7.12.7067

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