Article
Vulnerability of Antioxidant Drug Therapies on Targeting Nrf2-Trp53-Jdp2 Axis in Controlling the Tumorigenesis
2024-09-09
Abstract excerpt
Control of oxidation/antioxidation homeostasis is important for cellular protective functions, and disruption of the antioxidation balance by exogenous and endogenous ligands can lead to profound pathological consequences of cancerous commitment within cells. Although cancers are sensitive to antioxidation drugs, these drugs are sometimes associated with problems including tumor resistance or dose-limiting toxicit...
Topics
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- Antioxidant Activity and Oxidative Stress
- Cancer, Hypoxia, and Metabolism
- Free Radicals and Antioxidants
- Genomics, phytochemicals, and oxidative stress
- Glutathione Transferases and Polymorphisms
- Nanoplatforms for cancer theranostics
- Photodynamic Therapy Research Studies
- Phytochemicals and Antioxidant Activities
Identifiers and source
- Literature Corpus work
- 15b7fb4d-c34a-52ba-a92b-554262cc00f4
- DOI
- 10.20944/preprints202409.0612.v1