Article

Sepsis induces long-term reprogramming of human HSPCs and drives myeloid dysregulation in sepsis survivors

2024-12-17

Abstract excerpt

<h4>ABSTRACT</h4> Sepsis is a life-threatening condition characterised by an overwhelming immune response and high fatality. While most research has focused on its acute phase, many sepsis survivors remain immunologically weakened leaving them susceptible to serious complications from even mild infections. The mechanisms underlying this prolonged immune dysregulation remain unclear, limiting effective interventio...

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Literature Corpus work: 424844a8-ea9d-5f77-91bf-1c22e8d7c12c
DOI: 10.1101/2024.12.14.628447

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