Article

Neuronal IL-17 controls <i>C. elegans</i> developmental diapause through CEP-1/p53

2022-11-24

Abstract excerpt

During metazoan development, how cell division and metabolic programs are coordinated with nutrient availability remains unclear. Here, we show that nutrient availability signaled by the neuronal cytokine, ILC-17.1 switches C. elegans development between reproductive growth and dormancy by controlling the activity of the tumor suppressor p53 ortholog, CEP-1. Specifically, upon food availability, ILC-17.1 signalin...

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Literature Corpus work: 424277a4-b28e-52ab-9253-076229a52038
DOI: 10.1101/2022.11.22.517560

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