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Demographic and immune-based selection shifts before and after European contact inferred from 50 ancient and modern exomes from the Northwest Coast of North America

2016-04-29

Abstract excerpt

The susceptibility of Native Americans to infectious disease has been postulated as a major factor for their population decline after European contact. To investigate if a preexisting genetic component contributed to this phenomenon, we analyzed 50 exomes of both ancient and modern individuals from the Northwest Coast of North America, dating from before and after European contact. We confirmed the genetic continu...

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Literature Corpus work
4226967b-85a2-587f-a5d4-5eab4c54d2ab
DOI
10.1101/051078
Open publication

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Demographic and immune-based selection shifts before and after European contact inferred from 50 ancient and modern exomes from the Northwest Coast of North AmericaDOI 10.1101/051078
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