Article
Patterns of Genetic Coding Variation in a Native American Population before and after European Contact.
American journal of human genetics - 3 May 2018
Lindo John, Rogers Mary, Mallott Elizabeth K, Petzelt Barbara, Mitchell Joycelynn, Archer David, Cybulski Jerome S, Malhi Ripan S, DeGiorgio Michael
Abstract excerpt
The effects of European colonization on the genomes of Native Americans may have produced excesses of potentially deleterious features, mainly due to the severe reductions in population size and corresponding losses of genetic diversity. This assumption, however, neither considers actual genomic patterns that existed before colonization nor does it adequately capture the effects of admixture. In this study, we...
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