Article
A time transect of exomes from a Native American population before and after European contact.
Nature communications - 15 Nov 2016
Lindo John, Huerta-Sánchez Emilia, Nakagome Shigeki, Rasmussen Morten, Petzelt Barbara, Mitchell Joycelynn, Cybulski Jerome S, Willerslev Eske, DeGiorgio Michael, Malhi Ripan S
Abstract excerpt
A major factor for the population decline of Native Americans after European contact has been attributed to infectious disease susceptibility. To investigate whether a pre-existing genetic component contributed to this phenomenon, here we analyse 50 exomes of a continuous population from the Northwest Coast of North America, dating from before and after European contact. We model the population collapse after...
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