Article

Identification of dysregulated transcription factor activity in temporal lobe epilepsy

2025-04-25

Abstract excerpt

Approximately a third of patients with epilepsy continue to have uncontrolled seizures despite appropriate treatment with available antiseizure medications (i.e. drug-resistant epilepsy). There is emerging evidence that transcription factor (TF) activity is both dysregulated in epilepsy and modifiable by small molecule drugs, providing an opportunity for treatment innovation. Methods for identifying dysregulated T...

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Literature Corpus work: 41cfc30f-08bf-5ac9-aca4-79729e3bf6bf
DOI: 10.1101/2025.04.24.25326321

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