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Down-regulation of tumor suppressor miR-34a contributes to head and neck cancer by up-regulating MET oncogene and modulating tumor immune evasion

2020-08-25

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>MicroRNAs (miRs) have been shown to play an important role in tumorigenesis, including in head and neck squamous cell carcinoma (HNSCC). The miR-34a family is thought to play a role in tumor suppression, but the exact mechanism of action in HNSCC is not well understood. In addition, miR-34a is generally down-regulated HNSCC, but the role of chromosomal changes a...

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Literature Corpus work
41b439bb-2321-5f86-8253-37cc5c1c6cd8
DOI
10.21203/rs.3.rs-63977/v1
Open publication

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Down-regulation of tumor suppressor miR-34a contributes to head and neck cancer by up-regulating MET oncogene and modulating tumor immune evasionDOI 10.21203/rs.3.rs-63977/v1
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