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Article

Downregulation of microRNA-34 induces cell proliferation and invasion of human mesothelial cells

19 Mar 2013

Abstract excerpt

Malignant mesothelioma (MM) is an aggressive tumor with a dismal prognosis, and the molecular alterations involved in this disease remain unknown. We previously reported that microRNA-34s (miR-34s) are methylated and downregulated in MM and may play an important role in the carcinogenesis of MM. In this study, we downregulated miR-34s in human mesothelial cells to investigate the cellular effect of miR-34...

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PMID: 23525472
DOI: 10.3892/or.2013.2351

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