Article

Region-Specific PSD-95 Interactomes Contribute to Functional Diversity of Excitatory Synapses in Human Brain

2020-05-05

Abstract excerpt

The overarching goal of this exploratory study is to link subcellular microdomain specific protein-protein interactomes with big data analytics. We isolated postsynaptic density-95 (PSD-95) complexes from four human brain regions and compared their protein interactomes using multiple bioinformatics techniques. We demonstrate that human brain regions have unique postsynaptic protein signatures that may be used to i...

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Literature Corpus work: 41450f9c-d207-5d78-ba4d-59a1f2a952e5
DOI: 10.1101/2020.05.04.076844

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