Article

Comparing the signaling and transcriptome profiling landscapes of human iPSC-derived and primary rat neonatal cardiomyocytes

2022-09-06

Abstract excerpt

The inaccessibility of human cardiomyocytes significantly hindered years of cardiovascular research efforts. Post-mortem tissue or biopsies from diseased patients, which remain scarcely available, rendered it possible to study end-stage heart disease yet the inclusion of healthy human cardiac materials for basic science research was beyond reach. To overcome these limitations, non-human cell sources were used as p...

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Literature Corpus work: 41441b3b-ff9a-5a11-9e7e-c34db5e42c93
DOI: 10.1101/2022.09.06.506781

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